Publications at OSU


Prasadi C. Gallage, Mary G. McKee and Spencer P. Pitre*. 1,4-Dihydropyridine Anions as Potent Single-Electron Photoreductants. Organic Letters 2024, 26, 1975–1979.

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John Hayford G. Teye-Kau, Mayokun J. Ayodele and Spencer P. Pitre*. Vitamin B12-Photocatalyzed Cyclopropanation of Electron-Deficient Alkenes using Dischloromethane as a Methylene Source. Angewandte Chemie International Edition 2024, 63, e202316064.

Updated Graphical Abstract

Featured by OSU News and highlighted by OPR&D and Synfacts.


Prasadi C. Gallage and Spencer P. Pitre*. Direct photolysis of 4-tert-alkyl-1,4-dihydropyridines under blue-light irradiation for the generation of tertiary alkyl radicals. Green Chemistry 2022, 24, 6845–6848.



Tarannum Tasnim, Mayokun J. Ayodele and Spencer P. Pitre*. Recent Advances in Employing Catalytic Donors and Acceptors in Electron Donor-Acceptor Complex Photochemistry. Journal of Organic Chemistry 2022, 87, 10555–10563.

Synopsis TOC graphic


Spencer P. Pitre. Radical coupling decreases synthetic burden. Science 2022, 375, 1234. [Invited Perspective]


Tarannum Tasnim, Calvin Ryan, Miranda L. Christensen, Christopher J. Fennell and Spencer P. Pitre*. Radical Perfluoroalkylation Enabled by a Catalytically Generated Halogen Bonding Complex and Visible Light Irradiation. Organic Letters 2022, 24, 446–450.


Perfluoroalkylation TOC

                    Org Lett Cover                                      



Spencer P. Pitre* and Larry E. Overman*. Strategic Use of Visible-Light Photoredox Catalysis in Natural Product Synthesis. Chemical Reviews 2022, 122, 17171751.

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Part of the Photochemical Catalytic Processes Special Issue.


Publications Prior to OSU

17. Pitre, S. P.; Allred, T. K.; Overman, L. E. Lewis Acid Activation of Fragment-Coupling Reactions of Tertiary Carbon Radicals Promoted by Visible Light Irradiation of EDA Complexes. Organic Letters 2021, 23, 1103–1106. 
16. Pitre, S. P.; Muuronen, M.; Fishman, D. A.; Overman, L. E. Tertiary Alcohols as Radical Precursors for the Introduction of Tertiary Substituents into Heteroarenes. ACS Catalysis 2019, 9, 3413–3418.
15. Pitre, S. P.; Weires, N. A.; Overman, L. E. Forging C(sp3)–C(sp3) Bonds with Carbon-Centered Radicals in the Synthesis of Complex Molecules. Journal of the American Chemical Society 2019, 141, 2800–2813.
14. McCallum, T.; Pitre, S. P.; Morin, M.; Scaiano, J. C.; Barriault, L. The photochemical alkylation and reduction of heteroarenes. Chemical Science 2017, 8, 7412–7418.
13. Pitre, S. P.; Scaiano, J. C.; Yoon, T. P. Photocatalytic Indole Diels–Alder Cycloadditions Mediated by Heterogeneous Platinum-Modified Titanium Dioxide. ACS Catalysis 2017, 7, 6440–6444.
12. Pitre, S. P.; Yoon, T. P.; Scaiano, J. C. Titanium Dioxide Visible Light Photocatalysis: Surface Association Enables Photocatalysis with Visible Light Irradiation. Chemical Communications 2017, 53, 4335–4338.
11. Garcia, A. M., de Alwis Weerasekera, H.; Pitre, S. P.; McNeill, B.; Lissi, E.; Edwards, A. M.; Alarcon, E. M. Photodynamic performance of zinc phthalocyanine in HeLa cells: A comparison between DPCC liposomes and BSA as delivery systems. Journal of Photochemistry and Photobiology B: Biology 2016, 163, 385–390.
10. Pitre, S. P.; McTiernan, C. D.; Scaiano, J. C. Library of Cationic Organic Dyes for Visible-Light-Driven Photoredox Transformations. ACS Omega 2016, 1, 66–76.
9. Pitre, S. P.; McTiernan, C. D.; Scaiano, J. C. Understanding the Kinetics and Spectroscopy of Photoredox Catalysis and Transition-Metal Free Alternatives. Accounts of Chemical Research. 2016, 49, 1320–1330.
8. Pitre, S. P.; McTiernan, C. D.; Vine, W.; DiPucchio, R.; Grenier, M.; Scaiano, J. C. Visible-Light Actinometry and Intermittent Illumination as Convenient Tools to Study Ru(bpy)3Cl2 Mediated Photoredox Transformations. Scientific Reports 2015, 5, 16397.
7. Favrelle, A.; Gouhier, G.; Guillen, F.; Martin, C.; Mofaddel, N.; Petit, S.; Mundy, K. M.; Pitre, S. P.; Wagner, B. D. Structure-Binding Effects: Comparative Binding of 2-Anilino-6-naphthalenesulfonate by a Series of Alkyl- and Hydroxyalkyl-Substituted β-Cyclodextrins. Journal of Physical Chemistry B 2015, 119, 12921–12930.
6. McTiernan, C. D., Pitre, S. P., Scaiano, J. C. Photocatalytic Dehalogenation of Vicinal Dibromo Compounds Utilizing Sexithiophene and Visible-Light Irradiation. ACS Catalysis 2014, 4, 4034–4039.
5. McTiernan, C. D., Pitre, S. P., Ismail, H., Scaiano, J. C. Heterogeneous Light-Mediated Reductive Dehalogenations and Cyclizations Utilizing Platinum Nanoparticles on Titania (Pt@TiO2). Advanced Synthesis & Catalysis 2014, 356, 2819–2824.
4. Pitre, S. P., McTiernan, C. D., Ismaili, H., Scaiano, J. C. Metal-Free Photocatalytic Radical Trifluoromethylation Utilizing Methylene Blue and Visible Light Irradiation. ACS Catalysis 2014, 4, 2530–2535.
3. Pitre, S. P., McTiernan, C. D., Ismaili, H., Scaiano, J. C. Mechanistic Insights and Kinetic Analysis for the Oxidative Hydroxylation of Arylboronic Acids by Visible Light Photoredox Catalysis: A Metal-Free Alternative. Journal of the American Chemical Society 2013 135, 13286–13289.
2. Carter Ramirez, D. M., Pitre, S. P., Kim, Y. A., Bittman, R., Johnston, L. J. Photouncaging of Ceramides Promotes Reorganization of Liquid-Ordered Domains in Supported Lipid Bilayers. Langmuir 2013, 29, 3380–3387.
1. Ismaili, H., Pitre, S. P., Scaiano, J. C. Active participation of amine derived radicals in photoredox catalysis as exemplified by a reductive cyclization. Catalysis Science & Technology 2013, 3, 935–937.